H2N2V1, Main, Exploration, bibRecord, 002994

Host range recombinants of fowl plague (influenza A) virus

Identifieur interne : 002994 ( Main/Exploration ); précédent : 002993; suivant : 002995

Host range recombinants of fowl plague (influenza A) virus

Auteurs : C. Scholtissek [Allemagne] ; I. Koennecke [Allemagne] ; R. Rott [Allemagne]

Source :

Virology [ 0042-6822 ] ; 1978.

RBID : ISTEX:66437ED87AB66DBE381FC235EC980AC2A49E69FC

English descriptors

Teeft :
- Academic press, Chick, Chick embryo cells, Cytoplasmic extracts, Double infection, Embryo, Equi, Form plaques, Fowl, Fowl plague, Fowl plague virus, Gene coding, Gene constellation, Hemagglutinin, Hong kong, Hong kong strain, Host range, Host range recombinants, Influenza, Influenza virus, Influenza viruses, Mdbk cells, Mdck, Mdck cells, Mutant, Neuraminidase, Original host range, Pathogenic properties, Pathogenicity, Plaque, Plaque formation, Polymerase, Polymerase activity, Recombinant, Recombination, Rott, Scholtissek, Second recombination, Severe illness, Single gene, Viral, Virology.

Abstract

Abstract: Recombinants between the influenza virus strains fowl plague virus (FPV, Hav1N1) and Hong Kong (H3N2) have been isolated which form plaques on MDCK cells but not on chick embryo cells, although they carry the hemagglutinin of FPV. These host range recombinants have been characterized and one of them has been used for a second recombination with virus N (Hav2Neq1) or equi 2 (Heq2Neq2) on chick embryo cells. In this way, recombinants were obtained with a mixed genome which have regained the natural host range of FPV and some pathogenic properties for chicken. The results are discussed as a possible mechanism for a pandemic influenza strain to survive in an animal reservoir by changing its host range by recombination, and to regain the original host range by a second recombination but always keeping the same hemagglutinin.

Url:

https://api.istex.fr/ark:/67375/6H6-KKZS8BFH-N/fulltext.pdf

DOI: 10.1016/0042-6822(78)90356-2

Affiliations:

Allemagne

Links toward previous steps (curation, corpus...)

to stream Istex, to step Corpus: 000694
to stream Istex, to step Curation: 000694
to stream Istex, to step Checkpoint: 001584
to stream Main, to step Merge: 002B51
to stream Main, to step Curation: 002994

Le document en format XML

<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title>Host range recombinants of fowl plague (influenza A) virus</title>
<author><name sortKey="Scholtissek, C" sort="Scholtissek, C" uniqKey="Scholtissek C" first="C." last="Scholtissek">C. Scholtissek</name>
</author>
<author><name sortKey="Koennecke, I" sort="Koennecke, I" uniqKey="Koennecke I" first="I." last="Koennecke">I. Koennecke</name>
</author>
<author><name sortKey="Rott, R" sort="Rott, R" uniqKey="Rott R" first="R." last="Rott">R. Rott</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:66437ED87AB66DBE381FC235EC980AC2A49E69FC</idno>
<date when="1978" year="1978">1978</date>
<idno type="doi">10.1016/0042-6822(78)90356-2</idno>
<idno type="url">https://api.istex.fr/ark:/67375/6H6-KKZS8BFH-N/fulltext.pdf</idno>
<idno type="wicri:Area/Istex/Corpus">000694</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000694</idno>
<idno type="wicri:Area/Istex/Curation">000694</idno>
<idno type="wicri:Area/Istex/Checkpoint">001584</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">001584</idno>
<idno type="wicri:doubleKey">0042-6822:1978:Scholtissek C:host:range:recombinants</idno>
<idno type="wicri:Area/Main/Merge">002B51</idno>
<idno type="wicri:Area/Main/Curation">002994</idno>
<idno type="wicri:Area/Main/Exploration">002994</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a">Host range recombinants of fowl plague (influenza A) virus</title>
<author><name sortKey="Scholtissek, C" sort="Scholtissek, C" uniqKey="Scholtissek C" first="C." last="Scholtissek">C. Scholtissek</name>
<affiliation wicri:level="1"><country xml:lang="fr" wicri:curation="lc">Allemagne</country>
<wicri:regionArea>Institut für Virologie, Justus-Liebig-Universität, Giessen</wicri:regionArea>
<wicri:noRegion>Giessen</wicri:noRegion>
<wicri:noRegion>Giessen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Koennecke, I" sort="Koennecke, I" uniqKey="Koennecke I" first="I." last="Koennecke">I. Koennecke</name>
<affiliation wicri:level="1"><country xml:lang="fr" wicri:curation="lc">Allemagne</country>
<wicri:regionArea>Institut für Virologie, Justus-Liebig-Universität, Giessen</wicri:regionArea>
<wicri:noRegion>Giessen</wicri:noRegion>
<wicri:noRegion>Giessen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Rott, R" sort="Rott, R" uniqKey="Rott R" first="R." last="Rott">R. Rott</name>
<affiliation wicri:level="1"><country xml:lang="fr" wicri:curation="lc">Allemagne</country>
<wicri:regionArea>Institut für Virologie, Justus-Liebig-Universität, Giessen</wicri:regionArea>
<wicri:noRegion>Giessen</wicri:noRegion>
<wicri:noRegion>Giessen</wicri:noRegion>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Virology</title>
<title level="j" type="abbrev">YVIRO</title>
<idno type="ISSN">0042-6822</idno>
<imprint><publisher>ELSEVIER</publisher>
<date type="published" when="1978">1978</date>
<biblScope unit="volume">91</biblScope>
<biblScope unit="issue">1</biblScope>
<biblScope unit="page" from="79">79</biblScope>
<biblScope unit="page" to="85">85</biblScope>
</imprint>
<idno type="ISSN">0042-6822</idno>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0042-6822</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Academic press</term>
<term>Chick</term>
<term>Chick embryo cells</term>
<term>Cytoplasmic extracts</term>
<term>Double infection</term>
<term>Embryo</term>
<term>Equi</term>
<term>Form plaques</term>
<term>Fowl</term>
<term>Fowl plague</term>
<term>Fowl plague virus</term>
<term>Gene coding</term>
<term>Gene constellation</term>
<term>Hemagglutinin</term>
<term>Hong kong</term>
<term>Hong kong strain</term>
<term>Host range</term>
<term>Host range recombinants</term>
<term>Influenza</term>
<term>Influenza virus</term>
<term>Influenza viruses</term>
<term>Mdbk cells</term>
<term>Mdck</term>
<term>Mdck cells</term>
<term>Mutant</term>
<term>Neuraminidase</term>
<term>Original host range</term>
<term>Pathogenic properties</term>
<term>Pathogenicity</term>
<term>Plaque</term>
<term>Plaque formation</term>
<term>Polymerase</term>
<term>Polymerase activity</term>
<term>Recombinant</term>
<term>Recombination</term>
<term>Rott</term>
<term>Scholtissek</term>
<term>Second recombination</term>
<term>Severe illness</term>
<term>Single gene</term>
<term>Viral</term>
<term>Virology</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Abstract: Recombinants between the influenza virus strains fowl plague virus (FPV, Hav1N1) and Hong Kong (H3N2) have been isolated which form plaques on MDCK cells but not on chick embryo cells, although they carry the hemagglutinin of FPV. These host range recombinants have been characterized and one of them has been used for a second recombination with virus N (Hav2Neq1) or equi 2 (Heq2Neq2) on chick embryo cells. In this way, recombinants were obtained with a mixed genome which have regained the natural host range of FPV and some pathogenic properties for chicken. The results are discussed as a possible mechanism for a pandemic influenza strain to survive in an animal reservoir by changing its host range by recombination, and to regain the original host range by a second recombination but always keeping the same hemagglutinin.</div>
</front>
</TEI>
<affiliations><list><country><li>Allemagne</li>
</country>
</list>
<tree><country name="Allemagne"><noRegion><name sortKey="Scholtissek, C" sort="Scholtissek, C" uniqKey="Scholtissek C" first="C." last="Scholtissek">C. Scholtissek</name>
</noRegion>
<name sortKey="Koennecke, I" sort="Koennecke, I" uniqKey="Koennecke I" first="I." last="Koennecke">I. Koennecke</name>
<name sortKey="Rott, R" sort="Rott, R" uniqKey="Rott R" first="R." last="Rott">R. Rott</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/H2N2V1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002994 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 002994 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    H2N2V1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     ISTEX:66437ED87AB66DBE381FC235EC980AC2A49E69FC
   |texte=   Host range recombinants of fowl plague (influenza A) virus
}}

This area was generated with Dilib version V0.6.33.
Data generation: Tue Apr 14 19:59:40 2020. Site generation: Thu Mar 25 15:38:26 2021

	Serveur d'exploration H2N2
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration H2N2

Host range recombinants of fowl plague (influenza A) virus

Host range recombinants of fowl plague (influenza A) virus

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri